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Welcome to the PURPOSE Program Investigator Site

Thank you so much for working with us to help evaluate the safety and efficacy of investigational lenacapavir and emtricitabine/​tenofovir alafenamide for PrEP.

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Portals

Here are some resources and links to assist you with the study.

Firecrest Portal Signant Portal
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PURPOSE Presentations and Publications

Here are some links to the presentations and publications about the PURPOSE studies.

PURPOSE 1 - clinicaltrials.gov PURPOSE 2 - clinicaltrials.gov Pregnant and Lactating People in the Lenacapavir for HIV PrEP PURPOSE Program Global Consultation to Plan for Inclusion of Pregnant and Lactating Populations in a Phase 3 PrEP Clinical Trial Inclusion, Experience, and Data: Approaches for Prioritizing the Transgender and Gender-Diverse Voice in a Phase 3 Clinical Trial of Long-Acting PrEP Proactive strategies to optimize engagement of Black, Hispanic/Latinx, transgender, and nonbinary individuals in a trial of a novel agent for HIV pre-exposure prophylaxis (PrEP) Update on Gilead's HIV Prevention Trials presented at R4P 2021 Advancing Novel HIV Prevention Strategies, Together: A Scientific and Community Exchange presented at R4P 2021 Facilitating Next-Generation Pre-Exposure Prophylaxis Clinical Trials Using HIV Recent Infection Assays: A Consensus Statement from the Forum HIV Prevention Trial Design Project Sample size calculation for recency assay based clinical trials Using the F/TDF Adherence-Efficacy Relationship to Calculate Background HIV incidence

Community Inclusion Videos

Bringing the trial study sites to where the need is the greatest

Explore a video from Moupali Das, MD, MPH, the Executive Director of HIV Clinical Development at Gilead, as she describes why it was important that PURPOSE 2 add study sites in new locations in the country.

Video length: 1 min.

Inclusion from the start

Learn about how we think "Having everyone at the table makes the science better."

Video length: 1 min.

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